Ligand id: 4186

Name: ethylisopropylamiloride

Abbreviated name: EIPA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 136.51
Molecular weight 299.13
XLogP 0.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wilson AL, Womble SW, Prakash C, Cragoe EJ Jr, Blair IA, Limbird LE. (1992)
Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange.
Mol Pharmacol., 42: 175-179. [PMID:1325028]