[3H]CGS 21680

Ligand id: 424

Name: [3H]CGS 21680    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 6
Rotatable bonds 11
Topological polar surface area 197.74
Molecular weight 499.22
XLogP 2.12
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

References
1. Jarvis MF, Schulz R, Hutchison AJ, Do UH, Sills MA, Williams M. (1989)
[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.
J. Pharmacol. Exp. Ther.251 (3): 888-93. [PMID:2600819]
2. Wan W, Sutherland GR, Geiger JD. (1990)
Binding of the adenosine A2 receptor ligand [3H]CGS 21680 to human and rat brain: evidence for multiple affinity sites.
J. Neurochem.55 (5): 1763-71. [PMID:2213023]