[3H]CGS 21680

Ligand id: 424

Name: [3H]CGS 21680    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 6
Rotatable bonds 11
Topological polar surface area 197.74
Molecular weight 499.22
XLogP 2.12
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A2A receptor Agonist Full agonist 7.7 – 7.8 pKd - 1-2
pKd 7.7 – 7.8 (Kd 2.2x10-8 – 1.6x10-8 M) [1-2]
Ligand mentioned in the following text fields