Ligand id: 5168

Name: cinaciguat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 87.07
Molecular weight 565.28
XLogP 11.51
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Stasch JP, Schmidt P, Alonso-Alija C, Apeler H, Dembowsky K, Haerter M, Heil M, Minuth T, Perzborn E, Pleiss U et al.. (2002)
NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle.
Br. J. Pharmacol., 136 (5): 773-83. [PMID:12086987]