Ligand id: 5297

Name: zileuton

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 94.8
Molecular weight 236.06
XLogP 1.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Zouboulis ChC, Saborowski A, Boschnakow A. (2005)
Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum production.
Dermatology (Basel), 210 (1): 36-8. [PMID:15604543]