Ligand id: 6216

Name: AZ12216052

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 54.4
Molecular weight 391.06
XLogP 7.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Duvoisin RM, Pfankuch T, Wilson JM, Grabell J, Chhajlani V, Brown DG, Johnson E, Raber J. (2010)
Acute pharmacological modulation of mGluR8 reduces measures of anxiety.
Behav. Brain Res., 212 (2): 168-73. [PMID:20385173]