compound 11 [PMID: 20638279]

Ligand id: 6235

Name: compound 11 [PMID: 20638279]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 51.8
Molecular weight 197.1
XLogP 4.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. East SP, Bamford S, Dietz MG, Eickmeier C, Flegg A, Ferger B, Gemkow MJ, Heilker R, Hengerer B, Kotey A et al.. (2010)
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.
Bioorg. Med. Chem. Lett., 20 (16): 4901-5. [PMID:20638279]