Ligand id: 6339

Name: ramipril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 95.94
Molecular weight 416.23
XLogP 4.92
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Metzger H, Maier R, Sitter C, Stern HO. (1984)
2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S) -2-azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498)--a new and highly effective angiotensin I converting enzyme inhibitor.
Arzneimittelforschung, 34 (10B): 1402-6. [PMID:6097265]