lisinopril

Ligand id: 6360

Name: lisinopril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 13
Topological polar surface area 132.96
Molecular weight 405.23
XLogP 1.11
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Michaud A, Williams TA, Chauvet MT, Corvol P. (1997)
Substrate dependence of angiotensin I-converting enzyme inhibition: captopril displays a partial selectivity for inhibition of N-acetyl-seryl-aspartyl-lysyl-proline hydrolysis compared with that of angiotensin I.
Mol. Pharmacol.51 (6): 1070-6. [PMID:9187274]