Ligand id: 6457

Name: fosinoprilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 104.72
Molecular weight 435.22
XLogP 6.29
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. DeForrest JM, Waldron TL, Harvey C, Scalese B, Rubin B, Powell JR, Petrillo EW, Cushman DW. (1989)
Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology.
J. Cardiovasc. Pharmacol., 14 (5): 730-6. [PMID:2481187]