alfuzosin

Ligand id: 7109

Name: alfuzosin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 99.4
Molecular weight 389.21
XLogP 1.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Hieble JP. (2000)
Adrenoceptor subclassification: an approach to improved cardiovascular therapeutics.
Pharmaceutica Acta Helvetiae74: 163-171. [PMID:10812954]
2. Hieble JP, Bondinell WE, Ruffolo Jr RR. (1995)
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
J. Med. Chem.38 (18): 3415-44. [PMID:7658428]