estazolam

Ligand id: 7550

Name: estazolam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 43.07
Molecular weight 294.07
XLogP 4.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Dominguez RA, Goldstein BJ, Jacobson AF, Steinbook RM. (1986)
Comparative efficacy of estazolam, flurazepam, and placebo in outpatients with insomnia.
J Clin Psychiatry47 (7): 362-5. [PMID:2873132]
2. Post GL, Patrick RO, Crowder JE, Houston J, Ferguson JM, Bielski RJ, Bailey L, Pearlman HG, Shu VS, Pierce MW. (1991)
Estazolam treatment of insomnia in generalized anxiety disorder: a placebo-controlled study.
J Clin Psychopharmacol11 (4): 249-53. [PMID:1918423]