Ligand id: 7653

Name: ioflupane

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 29.54
Molecular weight 431.08
XLogP 4.86
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Antonini A, Benti R, De Notaris R, Tesei S, Zecchinelli A, Sacilotto G, Meucci N, Canesi M, Mariani C, Pezzoli G et al.. (2003)
123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.
Neurol. Sci., 24 (3): 149-50. [PMID:14598060]
2. Bajaj N, Hauser RA, Grachev ID. (2013)
Clinical utility of dopamine transporter single photon emission CT (DaT-SPECT) with (123I) ioflupane in diagnosis of parkinsonian syndromes.
J. Neurol. Neurosurg. Psychiatr., 84 (11): 1288-95. [PMID:23486993]
3. Treglia G, Cason E, Cortelli P, Gabellini A, Liguori R, Bagnato A, Giordano A, Fagioli G. (2014)
Iodine-123 metaiodobenzylguanidine scintigraphy and iodine-123 ioflupane single photon emission computed tomography in Lewy body diseases: complementary or alternative techniques?.
J Neuroimaging, 24 (2): 149-54. [PMID:23163913]