BX 471

Ligand id: 767

Name: BX 471

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 87.9
Molecular weight 434.15
XLogP 2.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Liang M, Mallari C, Rosser M, Ng HP, May K, Monahan S, Bauman JG, Islam I, Ghannam A, Buckman B, Shaw K, Wei GP, Xu W, Zhao Z, Ho E, Shen J, Oanh H, Subramanyam B, Vergona R, Taub D, Dunning L, Harvey S, Snider RM, Hesselgesser J, Morrissey MM, Perez HD. (2000)
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
J Biol Chem275: 19000-19008. [PMID:10748002]