Ligand id: 7711

Name: AZD6495

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.72
Molecular weight 441.2
XLogP 3.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Scott DA, Bell KJ, Campbell CT, Cook DJ, Dakin LA, Del Valle DJ, Drew L, Gero TW, Hattersley MM, Omer CA et al.. (2009)
3-amido-4-anilinoquinolines as CSF-1R kinase inhibitors 2: Optimization of the PK profile.
Bioorg. Med. Chem. Lett., 19 (3): 701-5. [PMID:19114305]