Ligand id: 7784

Name: CCG-50014

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 65.92
Molecular weight 316.07
XLogP 4.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Blazer LL, Zhang H, Casey EM, Husbands SM, Neubig RR. (2011)
A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins.
Biochemistry, 50 (15): 3181-92. [PMID:21329361]
2. Turner EM, Blazer LL, Neubig RR, Husbands SM. (2012)
Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins.
ACS Med Chem Lett, 3 (2): 146-150. [PMID:22368763]