BIX 02565

Ligand id: 8039

Name: BIX 02565

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 84.19
Molecular weight 458.24
XLogP 3.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Kirrane TM, Boyer SJ, Burke J, Guo X, Snow RJ, Soleymanzadeh L, Swinamer A, Zhang Y, Madwed JB, Kashem M et al.. (2012)
Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity.
Bioorg. Med. Chem. Lett., 22 (1): 738-42. [PMID:22056746]