Ligand id: 8095

Name: AC710

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 121.62
Molecular weight 562.33
XLogP 6.32
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Liu G, Campbell BT, Holladay MW, Ford Pulido JM, Hua H, Gitnick D, Gardner MF, James J, Breider MA, Brigham D et al.. (2012)
Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases.
ACS Med Chem Lett, 3 (12): 997-1002. [PMID:24900421]