compound 24 [PMID: 15955699]

Ligand id: 8131

Name: compound 24 [PMID: 15955699]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 110.92
Molecular weight 328.18
XLogP -0.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Bamford MJ, Bailey N, Davies S, Dean DK, Francis L, Panchal TA, Parr CA, Sehmi S, Steadman JG, Takle AK et al.. (2005)
(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: further optimisation as highly potent and selective MSK-1-inhibitors.
Bioorg. Med. Chem. Lett., 15 (14): 3407-11. [PMID:15955699]