compound 14 [PMID: 24900428]

Ligand id: 8154

Name: compound 14 [PMID: 24900428]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 76.24
Molecular weight 381.15
XLogP 2.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Huang H, Acquaviva L, Berry V, Bregman H, Chakka N, O'Connor A, DiMauro EF, Dovey J, Epstein O, Grubinska B et al.. (2012)
Structure-Based Design of Potent and Selective CK1γ Inhibitors.
ACS Med Chem Lett, 3 (12): 1059-64. [PMID:24900428]