compound 19a [PMID: 21855335]

Ligand id: 8186

Name: compound 19a [PMID: 21855335]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 103.24
Molecular weight 490.2
XLogP 2.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Zeng H, Belanger DB, Curran PJ, Shipps Jr GW, Miao H, Bracken JB, Arshad Siddiqui M, Malkowski M, Wang Y. (2011)
Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors.
Bioorg. Med. Chem. Lett., 21 (19): 5870-5. [PMID:21855335]