AM7

Ligand id: 8292

Name: AM7

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 73.36
Molecular weight 610.26
XLogP 6.64
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Bellon SF, Kaplan-Lefko P, Yang Y, Zhang Y, Moriguchi J, Rex K, Johnson CW, Rose PE, Long AM, O'Connor AB et al.. (2008)
c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations.
J. Biol. Chem.283 (5): 2675-83. [PMID:18055465]