compound 34 [PMID: 25974391]

Ligand id: 8396

Name: compound 34 [PMID: 25974391]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 115.02
Molecular weight 499.14
XLogP 2.86
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C et al.. (2016)
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
J. Med. Chem., 59 (4): 1642-7. [PMID:25974391]