compound 14 [PMID: 23634668]

Ligand id: 8557

Name: compound 14 [PMID: 23634668]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 91.32
Molecular weight 480.23
XLogP 5.96
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS et al.. (2013)
Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.
J. Med. Chem., 56 (10): 3996-4016. [PMID:23634668]