compound 7r [PMID: 26080733]

Ligand id: 8639

Name: compound 7r [PMID: 26080733]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 73.49
Molecular weight 473.22
XLogP 5.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Liu J, Peng X, Dai Y, Zhang W, Ren S, Ai J, Geng M, Li Y. (2015)
Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold.
Org. Biomol. Chem., 13 (28): 7643-54. [PMID:26080733]