compound 10h [PMID: 20832306]

Ligand id: 8779

Name: compound 10h [PMID: 20832306]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 144.99
Molecular weight 497.08
XLogP 3.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Tang H, Yan Y, Feng Z, de Jesus RK, Yang L, Levorse DA, Owens KA, Akiyama TE, Bergeron R, Castriota GA et al.. (2010)
Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities.
Bioorg. Med. Chem. Lett., 20 (20): 6088-92. [PMID:20832306]