compound 5z [PMID: 8410981]

Ligand id: 8893

Name: compound 5z [PMID: 8410981]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 98.19
Molecular weight 392.1
XLogP 1.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wall ME, Wani MC, Nicholas AW, Manikumar G, Tele C, Moore L, Truesdale A, Leitner P, Besterman JM. (1993)
Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.
J. Med. Chem., 36 (18): 2689-700. [PMID:8410981]