Ligand id: 8897

Name: AC-186

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 20.23
Molecular weight 306.12
XLogP 6.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. McFarland K, Price DL, Davis CN, Ma JN, Bonhaus DW, Burstein ES, Olsson R. (2013)
AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model.
ACS Chem Neurosci, 4 (9): 1249-55. [PMID:23898966]