example 13 [WO2009109743]

Ligand id: 9077

Name: example 13 [WO2009109743]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 80.24
Molecular weight 347.14
XLogP 4.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Pawsey S, Wood M, Browne H, Donaldson K, Christie M, Warrington S. (2016)
Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy Volunteers.
Drugs R D, 16 (2): 181-91. [PMID:26987975]
2. Roughley S, Walls S, Hart T, Parsons R, Brough P, Graham C, Macias A. (2009)
Azetidine derivatives.
Patent number: WO2009109743 A1. Assignee: Vernalis (R&D) Ltd.. Priority date: 04/03/2008. Publication date: 11/09/2009.