acumapimod

Ligand id: 9203

Name: acumapimod

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 113.8
Molecular weight 385.15
XLogP 3.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Ford PA. (2013)
Use of a pyrazole derivative in the treatment of acute exacerbations of chronic obstructive pulmonary disease.
Patent number: WO2013139809. Assignee: Novartis Ag. Priority date: 20/03/2012. Publication date: 26/09/2013.
2. Fryszman OM, Lang H, Lan J, Chang E, Fang Y. (2005)
5-membered heterocycle-based p38 kinase inhibitors.
Patent number: WO2005009973. Assignee: Novartis Ag. Priority date: 26/06/2003. Publication date: 03/02/2005.