pramipexole

Ligand id: 953

Name: pramipexole

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 79.18
Molecular weight 211.11
XLogP 1.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Mierau J, Schneider FJ, Ensinger HA, Chio CL, Lajiness ME, Huff RM. (1995)
Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors.
Eur J Pharmacol290: 29-36. [PMID:7664822]
2. Sautel F, Griffon N, Lévesque D, Pilon C, Schwartz JC, Sokoloff P. (1995)
A functional test identifies dopamine agonists selective for D3versus D2receptors.
Neuroreport6: 329-332. [PMID:7756621]