Compound class:
Synthetic organic
Comment: CORM-2 is a ruthenium-containing carbon monoxide (CO)-releasing pro-drug. CORM is an acronym for CO-releasing molecule. The therapeutic potential (antioxidant, anti-inflammatory, and anti-tumor properties) of such drugs is reviewed in [3].
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| References |
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1. Jiang L, Fei D, Gong R, Yang W, Yu W, Pan S, Zhao M, Zhao M. (2016)
CORM-2 inhibits TXNIP/NLRP3 inflammasome pathway in LPS-induced acute lung injury. Inflamm Res, 65 (11): 905-915. [PMID:27412237] |
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2. Lian S, Xia Y, Ung TT, Khoi PN, Yoon HJ, Kim NH, Kim KK, Jung YD. (2016)
Carbon monoxide releasing molecule-2 ameliorates IL-1β-induced IL-8 in human gastric cancer cells. Toxicology, 361-362: 24-38. [PMID:27393034] |
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3. Motterlini R, Mann BE, Foresti R. (2005)
Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Investig Drugs, 14 (11): 1305-18. [PMID:16255672] |
