Ligand Id: 2603
Ligand name astemizole

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 42.32
Molecular weight 458.25
XLogP 6.61
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

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Similar Ligands
ocaperidone
IUPHAR-DB targets
5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor
risperidone
IUPHAR-DB targets
α1A-adrenoceptor; α1B-adrenoceptor; α1D-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor; D3 receptor; H1 receptor
9-OH-risperidone
IUPHAR-DB targets
5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-ht1e receptor; H1 receptor
pirenperone
IUPHAR-DB targets
5-HT7 receptor
ritanserin
IUPHAR-DB targets
α1A-adrenoceptor; α1B-adrenoceptor; α1D-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor
iloperidone
IUPHAR-DB targets
5-HT1A receptor; 5-HT6 receptor; 5-HT7 receptor
L741742
GRAC targets
D4 receptor
IUPHAR-DB targets
D4 receptor
sertindole
IUPHAR-DB targets
5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT1F receptor; 5-HT2A receptor; 5-HT2C receptor; 5-ht1e receptor; H1 receptor
SB656104
GRAC targets
5-HT7 receptor
IUPHAR-DB targets
5-HT7 receptor