vasopressin

Ligand id: 2168

Name: vasopressin

Abbreviated name: AVP

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Approved drug? Yes (FDA (date of approval not specified))
IUPAC Name
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
International Nonproprietary Names
INN number INN
2144 vasopressin injection
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
AVP arginine vasopressin Human prepro-AVP-NP II (prepro-arginine-vasopressin-neurophysin II) ADH, antidiuretic hormone, ARVP, diabetes insipidus, neurohypophyseal, neurophysin II
Avp arginine vasopressin Mouse prepro-AVP-NP II (prepro-arginine-vasopressin-neurophysin II) Vp, Vsp
Avp arginine vasopressin Rat prepro-AVP-NP II (prepro-arginine-vasopressin-neurophysin II) Arginine vasopressin (Diabetes insipidus), arginine vasopressin (Diabetes insipidus) same as Di (conflicting physical mapping), arginine vasopressin (Diabetes insipidus), same as Di (conflicting physical mapping), Arginine vasopressin (Diabetes insipidus) same as Di (conflicting physical mapping), AVP-NPII, DI, prepropressophysin, preprovasopressin-neurophysin, Vas, vasopressin-neurophysin 2-copeptin, vasopressin-neurophysin prepropeptide
Synonyms
ADH | antidiuretic hormone | arginine vasopressin | argipressin
Database Links
CAS Registry No. 50-56-6
CATH/Gene3D 2.60.9.10
ChEBI CHEBI:34543
ChEMBL Ligand CHEMBL373742
DrugBank Ligand DB00067
PubChem CID 644077
Search Google for chemical match using the InChIKey KBZOIRJILGZLEJ-LGYYRGKSSA-N
Search Google for chemicals with the same backbone KBZOIRJILGZLEJ
Search PubMed clinical trials vasopressin injection
Search PubMed titles vasopressin injection
Search PubMed titles/abstracts vasopressin injection
Search UniChem for chemical match using the InChIKey KBZOIRJILGZLEJ-LGYYRGKSSA-N
Search UniChem for chemicals with the same backbone KBZOIRJILGZLEJ
UniProtKB P01186 (Rn), P35455 (Mm), P01185 (Hs)
Wikipedia Vasopressin
Comments
The approved drug is administered as an injection, as indicated by the INN.

As with all large peptide molecules, there is some ambiguity in representations of the stereochemistry of vasopressin, therefore the chemical structure shown here may differ slightly from that shown on other resouces linked to from the table above.