pranlukast

Ligand id: 3634

Name: pranlukast

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 119.09
Molecular weight 481.18
XLogP 7.62
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
International Nonproprietary Names
INN number INN
6943 pranlukast
Synonyms
ONO RS-411
Database Links
CAS Registry No. 103177-37-3
ChEMBL Ligand CHEMBL21333
DrugBank Ligand DB01411
GtoPdb PubChem SID 178100541
PubChem CID 4887
Search Google for chemical match using the InChIKey NBQKINXMPLXUET-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NBQKINXMPLXUET
Search PubMed clinical trials pranlukast
Search PubMed titles pranlukast
Search PubMed titles/abstracts pranlukast
Search UniChem for chemical match using the InChIKey NBQKINXMPLXUET-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NBQKINXMPLXUET
Wikipedia Pranlukast
Comments
Pranlukast is a leukotriene receptor antagonist (LTRA), with selectivity for cysteinyl leukotriene receptor 1 (CysLT1 receptor).