cladribine

Ligand id: 4799

Name: cladribine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 119.31
Molecular weight 285.06
XLogP -0.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
IUPAC Name
(2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
International Nonproprietary Names
INN number INN
6997 cladribine
Synonyms
Leustatin® | Litak®
Database Links
CAS Registry No. 4291-63-8
ChEMBL Ligand CHEMBL1619
DrugBank Ligand DB00242
PubChem CID 20279
RCSB PDB Ligand CL9
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Wikipedia Cladribine
Comments
Cladribine is a purine (adenosine) analogue and an antineoplastic and immunosuppressant agent