propranolol

Ligand id: 564

Name: propranolol

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View more information in the IUPHAR Pharmacology Education Project: propranolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 41.49
Molecular weight 259.16
XLogP 4.05
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1967))
IUPAC Name
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
International Nonproprietary Names
INN number INN
1940 propranolol
Synonyms
Bedranol® | Inderal® | propranolol hydrochloride
Database Links
BindingDB Ligand 25761
CAS Registry No. 525-66-6 (source: ChEBI)
ChEBI CHEBI:8499
ChEMBL Ligand CHEMBL27
DrugBank Ligand DB00571
PubChem CID 4946
Search Google for chemical match using the InChIKey AQHHHDLHHXJYJD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AQHHHDLHHXJYJD
Search PubMed clinical trials propranolol
Search PubMed titles propranolol
Search PubMed titles/abstracts propranolol
Search UniChem for chemical match using the InChIKey AQHHHDLHHXJYJD-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AQHHHDLHHXJYJD
Wikipedia Propranolol
Comments
The approved drug propranolol is a racemic mixtue of (+)-propranolol and (-)-propranolol. We show the non-stereo molecule to represent the mixture.