Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (1983))

IUPAC Name

(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one

International Nonproprietary Names
INN number	INN
3835	etoposide

Synonyms

(-)-etoposide | Etopophos® | Toposar® | trans-etoposide | VePesid® | VP 16-213 | VP-16

Comments

A DNA topoisomerase II inhibitor which is a synthetic derivative of podophyllotoxin, found in the American Mayapple (Podophyllum peltatum).

Database Links
CAS Registry No.	33419-42-0
ChEBI	CHEBI:4911
ChEMBL Ligand	CHEMBL44657
DrugBank Ligand	DB00773
GtoPdb PubChem SID	178103421
PubChem CID	36462
RCSB PDB Ligand	EVP
Search Google for chemical match using the InChIKey	VJJPUSNTGOMMGY-MRVIYFEKSA-N
Search Google for chemicals with the same backbone	VJJPUSNTGOMMGY
Search PubMed clinical trials	etoposide
Search PubMed titles	etoposide
Search PubMed titles/abstracts	etoposide
Search UniChem for chemical match using the InChIKey	VJJPUSNTGOMMGY-MRVIYFEKSA-N
Search UniChem for chemicals with the same backbone	VJJPUSNTGOMMGY
Wikipedia	Etoposide

Product suppliers

Etoposide Cat. No. 1226