tolazamide

Ligand id: 6847

Name: tolazamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 86.89
Molecular weight 311.13
XLogP 3.19
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1986))
IUPAC Name
1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea
International Nonproprietary Names
INN number INN
1296 tolazamide
Synonyms
tolazolamide | Tolinase®
Database Links
CAS Registry No. 1156-19-0
ChEMBL Ligand CHEMBL817
DrugBank Ligand DB00839
PubChem CID 5503
Search Google for chemical match using the InChIKey OUDSBRTVNLOZBN-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey OUDSBRTVNLOZBN-UHFFFAOYSA-N
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Wikipedia Tolazamide
Comments
A sulfonylurea family drug inhibiting sulfonylurea receptor 1 (ABCC8)/Kir6.2 (KCNJ11) potassium channel activity.