temozolomide

Ligand id: 7301

Name: temozolomide

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: temozolomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 81.22
Molecular weight 194.06
XLogP -1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA and FDA (1999))
IUPAC Name
3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
International Nonproprietary Names
INN number INN
6027 temozolomide
Synonyms
CCRG-81045 | M-39831 | Temodal® | Temodar®
Database Links
CAS Registry No. 85622-93-1
ChEMBL Ligand CHEMBL810
DrugBank Ligand DB00853
PubChem CID 5394
Search Google for chemical match using the InChIKey BPEGJWRSRHCHSN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BPEGJWRSRHCHSN
Search PubMed clinical trials temozolomide
Search PubMed titles temozolomide
Search PubMed titles/abstracts temozolomide
Search UniChem for chemical match using the InChIKey BPEGJWRSRHCHSN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BPEGJWRSRHCHSN
Wikipedia Temozolomide
Comments
Temozolomide is a DNA alkylating agent.