lenvatinib

Ligand id: 7426

Name: lenvatinib

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 115.57
Molecular weight 426.11
XLogP 2.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA & EMA (2015))
IUPAC Name
4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
International Nonproprietary Names
INN number INN
9361 lenvatinib
Synonyms
E 7080 | ER-203492-00 | Lenvima®
Database Links
CAS Registry No. 417716-92-8 (source: Scifinder)
ChEMBL Ligand CHEMBL1289601
PubChem CID 9823820
RCSB PDB Ligand LEV
Search Google for chemical match using the InChIKey WOSKHXYHFSIKNG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WOSKHXYHFSIKNG
Search PubMed clinical trials lenvatinib
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Search UniChem for chemical match using the InChIKey WOSKHXYHFSIKNG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WOSKHXYHFSIKNG
SynPHARM 79689 (in complex with kinase insert domain receptor)
Wikipedia Lenvatinib
Comments
Lenvatinib is a potent inhibitor of VEGFR-2 (KDR) and VEGFR-3 (FLT4) [1].