capmatinib

Ligand id: 7904

Name: capmatinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 85.07
Molecular weight 412.14
XLogP 3.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide
International Nonproprietary Names
INN number INN
9948 capmatinib
Synonyms
INC280 | INCB28060
Database Links
CAS Registry No. 1029712-80-8
ChEMBL Ligand CHEMBL3188267
GtoPdb PubChem SID 249565587
PubChem CID 25145656
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Comments
Capmatinib (NCB28060) is a novel, ATP-competitive inhibitor of c-MET [1].