compound 2c [PMID: 24900538]

Ligand id: 8138

Name: compound 2c [PMID: 24900538]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 93.54
Molecular weight 381.17
XLogP 4.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine
Database Links
ChEMBL Ligand CHEMBL2151321
PubChem CID 59627005
Search Google for chemical match using the InChIKey FZBVNCFBCNXULH-LBPRGKRZSA-N
Search Google for chemicals with the same backbone FZBVNCFBCNXULH
Search UniChem for chemical match using the InChIKey FZBVNCFBCNXULH-LBPRGKRZSA-N
Search UniChem for chemicals with the same backbone FZBVNCFBCNXULH
Comments
Compound 2c is one of the analogues identified by a medicinal chemistry approach to identify neurotrophic tyrosine kinase, receptor, type 1 (TrkA) inhibitors [1].