cmp5 [PMID: 25742700]

Ligand id: 8288

Name: cmp5 [PMID: 25742700]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 29.85
Molecular weight 315.17
XLogP 4.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(9-ethylcarbazol-3-yl)-N-(pyridin-3-ylmethyl)methanamine
Synonyms
ChemBridge ID 9033823 [1]
Database Links
GtoPdb PubChem SID 252166500
PubChem CID 4722575
Search Google for chemical match using the InChIKey GAVUWQFIRGBDHN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GAVUWQFIRGBDHN
Search UniChem for chemical match using the InChIKey GAVUWQFIRGBDHN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GAVUWQFIRGBDHN
Comments
cmp5 is reported as a novel, first-in-class, selective small molecule inhibitor of PRMT5 [1], an arginine methyltransferase (RMT) of the histone methyltransferase (HMT) family.