safinamide

Ligand id: 8291

Name: safinamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 64.35
Molecular weight 302.14
XLogP 3.07
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2015), FDA (2017))
IUPAC Name
(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide
International Nonproprietary Names
INN number INN
8013 safinamide
Synonyms
EMD 1195686 | EMD-1195686 | Xadago®
Database Links
CAS Registry No. 133865-89-1
ChEMBL Ligand CHEMBL396778
PubChem CID 131682
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SynPHARM 81929 (in complex with Monoamine oxidase B)
81928 (in complex with Monoamine oxidase B)
Wikipedia Safinamide
Comments
Safinamide is an alpha-aminoamide. The clinically administered formulation may be the mesylate salt (PubChem CID 3038502).