AZD8330

Ligand id: 8474

Name: AZD8330

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 90.9
Molecular weight 461.02
XLogP 2.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide
Synonyms
ARRY-424704 | ARRY-704 | AZD-8330
Database Links
CAS Registry No. 869357-68-6
ChEMBL Ligand CHEMBL3182621
PubChem CID 16666708
Search Google for chemical match using the InChIKey RWEVIPRMPFNTLO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RWEVIPRMPFNTLO
Search UniChem for chemical match using the InChIKey RWEVIPRMPFNTLO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RWEVIPRMPFNTLO
Comments
AZD8330 is a non-ATP competitive inhibitor of the kinases MEK 1 and MEK2.