AS1949490

Ligand id: 8878

Name: AS1949490

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 66.57
Molecular weight 371.07
XLogP 6.44
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(4-chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
Synonyms
AS 1949490 | AS-1949490
Database Links
CAS Registry No. 1203680-76-5
ChEMBL Ligand CHEMBL2337806
PubChem CID 44473434
Search Google for chemical match using the InChIKey RFZPGNRLOKVZJY-AWEZNQCLSA-N
Search Google for chemicals with the same backbone RFZPGNRLOKVZJY
Search UniChem for chemical match using the InChIKey RFZPGNRLOKVZJY-AWEZNQCLSA-N
Search UniChem for chemicals with the same backbone RFZPGNRLOKVZJY
Comments
AS1949490 is a small molecule inhibitor of SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2, a.k.a. inositol polyphosphate phosphatase-like 1, with gene symbol INPPL1) [1] which can be used as a tool compound to elucidate the normal and pathophysiological roles of SHIP2.