CYP2B6

Target id: 1324

Nomenclature: CYP2B6

Family: CYP2 family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for CYP2B6 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - CYP2B6 cytochrome P450 family 2 subfamily B member 6
Previous and Unofficial Names
cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 | 1,4-cineole 2-exo-monooxygenase | cytochrome P450, family 2, subfamily B, polypeptide 6
Database Links
BRENDA
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 1.14.14.1

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
ticlopidine Hs Inhibition 6.7 pIC50 1
pIC50 6.7 (IC50 2x10-7 M) [1]

References

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1. Fontana E, Dansette PM, Poli SM. (2005) Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr. Drug Metab.6 (5): 413-54. [PMID:16248836]

How to cite this page

CYP2 family: CYP2B6. Last modified on 16/09/2015. Accessed on 14/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1324.