protein kinase AMP-activated non-catalytic subunit beta 2 | AMPK subfamily | IUPHAR/BPS Guide to PHARMACOLOGY

protein kinase AMP-activated non-catalytic subunit beta 2

Target id: 1544

Nomenclature: protein kinase AMP-activated non-catalytic subunit beta 2

Abbreviated Name: AMPKB2

Family: AMPK subfamily

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for protein kinase AMP-activated non-catalytic subunit beta 2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 272 1q21.2 PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
Mouse - 271 3 F2.2 Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
Rat - 271 2q34 Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2
Previous and Unofficial Names
AMP-activated protein kinase beta-2 regulatory subunit | AMPK subunit beta-2 | protein kinase
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

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Allosteric Modulators
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
MT47-100 Hs Negative 4.6 pKi 1
pKi 4.6 (Ki 2.48x10-5 M) [1]

References

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1. Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE et al.. (2015) Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release. Chem. Biol., 22 (6): 705-11. [PMID:26091167]

How to cite this page

AMPK subfamily: protein kinase AMP-activated non-catalytic subunit beta 2. Last modified on 30/03/2016. Accessed on 14/11/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1544.