Interleukin-18 receptor 1

Target id: 1737

Nomenclature: Interleukin-18 receptor 1

Family: Immunoglobulin-like family of IL-1 receptors

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin-18 receptor 1 has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-18 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 541 02q12.1 IL18R1 interleukin 18 receptor 1
Mouse 1 537 Il18r1 interleukin 18 receptor 1
Rat - - Il18r1 interleukin 18 receptor 1
Previous and Unofficial Names
CD218a | Il18ralpha | IL1RRP | interleukin 18 receptor 1
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interleukin-18 1 protein (IL18R1) is the ligand binding subunit of the functional IL-18 receptor heterodimer.
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  T-helper 1 cell differentiation (GO:0045063) IEA
References: 
Immuno Process:  T cell (activation)
Immuno Process ID:  4
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  T-helper 1 cell differentiation (GO:0045063) IEA
References: 
Immuno Process:  B cell (activation)
Immuno Process ID:  5
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  T-helper 1 cell differentiation (GO:0045063) IEA
References: 
Immuno Process:  Immune system development
Immuno Process ID:  8
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  T-helper 1 cell differentiation (GO:0045063) IEA
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  interleukin-1 receptor activity (GO:0004908) IEA
positive regulation of interferon-gamma production (GO:0032729) IEA
interleukin-18 receptor activity (GO:0042008) IEA
References: 
Immuno Process:  Cellular signalling
Immuno Process ID:  11
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  natural killer cell activation (GO:0030101) IEA
T-helper 1 cell differentiation (GO:0045063) IEA
References: 

How to cite this page

Immunoglobulin-like family of IL-1 receptors: Interleukin-18 receptor 1. Last modified on 30/10/2017. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1737.